Helps significantly lower the HP regen from Chemical Rage with Soul Release charges.
Helps significantly lower the HP regen on Axe with Soul Release charges and make it easier to burst him down.
Pick up an early Vessel so you have some healing reduction for Bloodseeker, before your cores are able to acquire the more expensive Skadi in Shiva to further reduce his healing.
Helps significantly lower Bristlebacks HP regen with Soul Release charges. Particularly useful against Bloodstone.
Helps significantly lower the lifesteal from Insatiable Hunger with Soul Release charges.
Helps significantly lower the HP regen on Centaur with Soul Release charges and make it easier to burst him down.
Helps significantly lower Chen's healing from his ultimate with Soul Release charges.
Helps significantly lower the HP gain from Luminosity and reduce her healing through Solar Guardian with Soul Release charges.
Helps lower the healing from Dazzle through Shadow Wave and sustain items.
Helps significantly lower the healing from Spirit Siphon and at the end of Exorcism.
Helps significantly lower the HP regen on Doom with Soul Release charges and make it easier to burst him down.
Helps significantly lower the HP regen from Dragon Blood with Soul Release charges.
Helps lower the healing from Enchantress with Natures Attendants.
Helps significantly lower the HP gain from Time Walk with Soul Release charges.
Helps significantly lower the HP regen from Berserker's Blood with Soul Release charges.
Helps significantly lower the healing and HP regen from Tether and Overcharge with Soul Release charges.
Helps significantly lower the HP regen on Kunkka with Soul Release charges and make it easier to burst him down.
Helps significantly lower the spell lifesteal from Bloodstone usage with Soul Release charges.
Helps significantly lower the lifesteal on Lone Druid from Spirit Link with Soul Release charges.
Helps significantly lower the lifesteal on Luna from Mask of Madness or Satanic with Soul Release charges.
Helps significantly lower the lifesteal from Sidekick and Bodyguard with Soul Release charges.
Helps significantly lower the HP gain from Ransack with Soul Release charges.
Helps significantly lower the lifesteal from Jingu Mastery attacks with Soul Release charges.
Helps significantly lower the HP gain from Attribute Shift (Strength Gain) with Soul Release charges.
Helps significantly lower the healing and HP regen from Death Pulse and Heartstopper Aura with Soul Release charges.
Helps significantly lower the healing from Purification with Soul Release charges.
Helps significantly lower the healing from Purifying Flames with Soul Release charges. Look to apply Spirit Vessel near the end of False Promise.
Helps significantly lower the HP regen on Pudge with Soul Release charges and make it easier to burst him down.
Significantly reduces HP regen and gives you multiple instances of damage over time to eat away Templar Assassin's Refraction charges.
Helps significantly lower the HP regen from Reactive Armor stacks with Soul Release charges.
Helps significantly lower the HP regen on Underlord with Soul Release charges and make it easier to burst him down.
Gives you multiple instances of damage over time to help eat away the Gravekeeper's Cloak layers. Helps significantly lower the HP regen from Stone Form on Visage once he has Aghanims Shard.
Helps significantly lower the lifesteal from Vampiric Spirit with Soul Release charges.