Doom's Doom is usually dealt with by retreating and hiding somewhere in safety until it expires. Bloodseeker can provide global vision of the Doomed target with Thirst and quickly catch up to it to secure the kill. Both Rupture and Doom do Pure Damage and the combination of the two completely cripples a target, sentencing it to its "doom".

Doom's Doom is usually dealt with by retreating and hiding somewhere in safety until it expires. Charge of Darkness provides global follow up damage and vision of the Doomed target to secure the kill, allowing Doom to ult more freely and more often as he has consistent follow up from Spirit Breaker. Both Nether Strike and Charge of Darkness proc Greater Bash, that can interrupt any Doomed targets that are trying to TP out to safety even if they have Debuff Immunity.

Doom's Doom is usually dealt with by retreating and hiding somewhere in safety until it expires. Spectre provides global follow up damage and vision of the Doomed target with Shadow Step and Spectral Dagger to secure the kill, allowing Doom to ult more freely and more often as he has consistent follow up from Spectre.

The two pair well in lane as they are melee/ranged. Soul Bind works with Doom, doubling its effect. Infernal Blade and War Stomp, which Doom can acquire trough Devouring a Centaur Conqueror, can set up Ink Swell, while Scorched Earth helps Doom catch up and stick to his target.

Doom's Doom is usually dealt with by retreating and hiding somewhere in safety until it expires. Thundergod's Wrath and Nimbus (Aghanim's Scepter Upgrade) provide global follow up damage and vision of the Doomed target to secure the kill, allowing Doom to ult more freely and more often as he has consistent follow up from Zeus. Nimbus can additionally interrupt any Doomed targets that are trying to TP out to safety.

Doom's Doom negates Chemical Rage's healing completely, which is Alch's main defensive tool. This usually forces Alch to flee from the fight entirely and wait it out. He can Devour a Vhoul Assassin neutral to almost entirely decrease Chemical Rage's sustain outside of Doom.

Doom's ultimate essentially takes Axe out of the game for a period of time. When put on autocast his Infernal Blade can trigger during Berserker's Call stunning Axe briefly and doing Max HP percentage damage.

Doom's ult - Doom completely negates Leshrac's sustain in fights, crippling him significantly and forces him to flee the fight altogether or risk getting bursted. He's a natural Shiva builder and can Devour a Vhoul Assassin, which makes him greatly effective even outside of Doom.

Necro's main mechanic is healing trough Death Pulse, Death Seeker (Aghanim's Shard Upgrade) and Sadist stacks, which Doom completely prevents. Doom can Devour several creeps and use them against Necro - some of the more notable ones are: Satyr Banisher to Purge Ghost Shroud; Centaur Courser for Cloak Aura, which is a Magic Resistance AURA (basically Pipe but twice as better); Vhoul Assassin for Envenomed Weapon to almost entirely reduce Sadist's and general HP regen.

Doom is able to prevent Spectre from receiving any heals by using his ult - Doom on her, effectively removing her from the fight. In lane, he is able to reliably pressure her with all 3 of his basic spells if he finds a suitable neutral creep. Additionally, as the game goes on Doom can enhance his ult with Break.

Tempest Double allows Arc to fight even when Doomed, diminishing Doom's impact. His Magnetic Field provides evasion for him and his team making Infernal Blade clunky to use due to Doom's increased attack range. Arc's split pushing and kiting potential make it hard for Doom to control him, effectively countering Doom's single-target, ultimate-dependant playstyle.

Divided we Stand allows Meepo to keep most of his impact even when Doomed. Most importantly, Megameepo (Aghanim's Scepeter Upgrade) allows Meepo Prime to save any of his Meepo's from Doom and completely prevent the Doomed Meepo from receiving any damage for its duration from any source other than Doom. This greatly complicates Doom's gameplay as post Aghanim's Scepeter he is forced to Doom Meepo Prime, who can just stay back and Poof himself onto the Doomed Meepo to save him.

Mana Shield does not take into account any Armor or Magic Resistance, making it the perfect counter to Doom's Pure Damage. Cold Blooded (Aghanim's Shard Upgrade) when combined with Aghanim's Scepeter allows Dusa to stun Doom upon casting Doom and naturally create distance. Doom lacks Mana Burn and the Attack Speed to justify a Diffusal/Disperser and struggles greatly to get trough Dusa's Manapool.

If you Doom the Spirit Bear LD can just resummon it if it happens to die, if you Doom LD then the Spirit Bear runs rampant. True Form's transformation time does not get interrupted by Doom and is not considered a heal, providing its HP bonus despite Doom's healing negation.

Spell Steal allows Rubick to cast a significantly improved version of Doom as it increases its duration and damage greatly, while reducing its cooldown. Telekinesis once improved with Aghanim's Shard can be used as a pseudo save for any Doomed targets and reposition them to safety.